Next-Generation of Allergen-Specific Immunotherapies: Molecular Approaches

Next generation molecular ecology.

Calling a special issue of Molecular Ecology that deals with next-generation sequencing 'Next generation Molecular Ecology' seems to be all too obvious. However, as the contributions to this issue came in, it became increasingly clear that next-generation sequencing (NGS) is more than just a technical leap – it will result in a transformation of how we think about molecular ecology as a discipl...

Allergen hybrids – next generation vaccines for Fagales pollen immunotherapy

BACKGROUND Trees belonging to the order of Fagales show a distinct geographical distribution. While alder and birch are endemic in the temperate zones of the Northern Hemisphere, hazel, hornbeam and oak prefer a warmer climate. However, specific immunotherapy of Fagales pollen-allergic patients is mainly performed using birch pollen extracts, thus limiting the success of this intervention in bi...

AI approaches for next generation telecommunication networks

Genome Walking by Next Generation Sequencing Approaches

Genome Walking (GW) comprises a number of PCR-based methods for the identification of nucleotide sequences flanking known regions. The different methods have been used for several purposes: from de novo sequencing, useful for the identification of unknown regions, to the characterization of insertion sites for viruses and transposons. In the latter cases Genome Walking methods have been recentl...

Review: allergen-specific immunotherapies reduce symptoms, medication requirements, and bronchial hyperreactivity in asthma.

and commentary also appear in ACP Journal Club. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . For correspondence: Associate Professor M Abramson, Monash University, Prahran, Victoria, Australia. [email protected] Source of funding: Garfield Weston Foundation, UK. Commentary T he updated review by Abrams...